Friday, September 7, 2012

Portraits from the frontline: Syrian rebels pose

Muhammed Muheisen / AP

Ammar Aldeerani, 21, a defected soldier from the Syrian security forces

As they waited to return to the fight against government forces, rebels at a house in Marea on the outskirts of Aleppo posed for portraits for AP photographer Muhammed Muheisen. In their former lives, before the war, they were a construction worker, a farmer, even a librarian. Two of them are former government soldiers.?

Muhammed Muheisen / AP

Hamzah Alhassan, 25, a former blacksmith

Muhammed Muheisen / AP

Abu Muslim, 30, a former librarian

Muhammed Muheisen / AP

Shadi Farrouh, 28, a former construction worker

Muhammed Muheisen / AP

Abu Faris, 28, a defected officer from the Syrian security forces

Muhammed Muheisen / AP

Ahmad Hussein, 22, a former factory worker

Muhammed Muheisen / AP

Abu Bara', 30, a former farmer

Goran Tomasevic / Reuters

After months of protests and violent crackdowns, a look back at the violence that has overtaken the country.

?

Source: http://photoblog.nbcnews.com/_news/2012/09/06/13709868-portraits-from-the-frontline-syrian-rebels-pose-in-aleppo?lite

masters par 3 gwen stefani overeem laron landry mary j blige burger king islands joe flacco

Standard chemotherapy provides higher survival rate than experimental in lung cancer patients

Standard chemotherapy provides higher survival rate than experimental in lung cancer patients [ Back to EurekAlert! ] Public release date: 6-Sep-2012
[ | E-mail | Share Share ]

Contact: Michelle Kirkwood
michellek@astro.org
American Society for Radiation Oncology

Treatment with pemetrexed, carboplatin and bevacizumab followed by maintenance pemetrexed and bevacizumab (Pem+Cb+B) is no better than standard therapy with paclitaxel, carboplatin and bevacizumab followed by bevacizumab (Pac+Cb+B) in patients with advanced non-squamous non-small cell lung cancer (NS-NSCLC), according to research presented at the 2012 Chicago Multidisciplinary Symposium in Thoracic Oncology. This symposium is sponsored by the American Society of Clinical Oncology (ASCO), the American Society for Radiation Oncology (ASTRO), the International Association for the Study of Lung Cancer (IASLC) and The University of Chicago.

According to the American Cancer Society, lung cancer is the number one cause of cancer deaths in men and women each year. The current standard treatment for advanced NS-NSCLC patients, the most common form of advanced NSCLC, is either Pac+Cb+B or pemetrexed plus cisplatin. This trial sought to define a new standard of care by comparing Pac+Cb+B to the experimental chemotherapy regimen Pem+Cb+B to determine if either improved overall survival for late-stage lung cancer patients. Pemetrexed plus cisplatin was not tested in this trial.

The 939 patients were randomized to receive one of the two treatment arms every three weeks for up to four cycles. The patients received the same arm for each cycle. Overall survival was not statistically different between the two arms, 12.6 months in Pem+Cb+ Bev versus 13.4 months for the Pac+Cb+B arm, The experimental arm of Pem+Cb+Bev led to a increase in time before progression of disease (PFS) compared with the standard arm of Pac+ Cb+Bev6 months versus 5.6 months, respectively.

"The fact that there was no improvement in survival with the experimental regimen was disappointing, but these findings are important as we continue to navigate ways to improve survival for this devastating disease," said Jyoti Patel, MD, lead author of the study and an associate professor in Medicine-Hematology/Oncology at Northwestern University in Chicago. "It is important to note that both regimens demonstrated tolerability, although their toxicities differed. These differences can be important for our patients."

###

The abstract, "A Randomized, Open-label, Phase 3, Superiority Study of Pemetrexed (Pem) + Carboplatin (Cb) + Bevacizumab (B) Followed by Maintenance Pem + B versus Paclitaxel (Pac) + Cb + B Followed by Maintenance B in Patients (pts) with Stage IIB or IV Non-squamous Non-small Cell Lung Cancer (NS-NSCLC)," will be presented during the Plenary Session at 12:30 p.m., Central time on September 7, 2012. To speak with Jyoti Patel, MD, please call Michelle Kirkwood or Nicole Napoli on September 6-8, 2012, in the press office at the Chicago Marriott Downtown Magnificent Mile at 312-595-3188. You may also email them at michellek@astro.org or nicolen@astro.org.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Standard chemotherapy provides higher survival rate than experimental in lung cancer patients [ Back to EurekAlert! ] Public release date: 6-Sep-2012
[ | E-mail | Share Share ]

Contact: Michelle Kirkwood
michellek@astro.org
American Society for Radiation Oncology

Treatment with pemetrexed, carboplatin and bevacizumab followed by maintenance pemetrexed and bevacizumab (Pem+Cb+B) is no better than standard therapy with paclitaxel, carboplatin and bevacizumab followed by bevacizumab (Pac+Cb+B) in patients with advanced non-squamous non-small cell lung cancer (NS-NSCLC), according to research presented at the 2012 Chicago Multidisciplinary Symposium in Thoracic Oncology. This symposium is sponsored by the American Society of Clinical Oncology (ASCO), the American Society for Radiation Oncology (ASTRO), the International Association for the Study of Lung Cancer (IASLC) and The University of Chicago.

According to the American Cancer Society, lung cancer is the number one cause of cancer deaths in men and women each year. The current standard treatment for advanced NS-NSCLC patients, the most common form of advanced NSCLC, is either Pac+Cb+B or pemetrexed plus cisplatin. This trial sought to define a new standard of care by comparing Pac+Cb+B to the experimental chemotherapy regimen Pem+Cb+B to determine if either improved overall survival for late-stage lung cancer patients. Pemetrexed plus cisplatin was not tested in this trial.

The 939 patients were randomized to receive one of the two treatment arms every three weeks for up to four cycles. The patients received the same arm for each cycle. Overall survival was not statistically different between the two arms, 12.6 months in Pem+Cb+ Bev versus 13.4 months for the Pac+Cb+B arm, The experimental arm of Pem+Cb+Bev led to a increase in time before progression of disease (PFS) compared with the standard arm of Pac+ Cb+Bev6 months versus 5.6 months, respectively.

"The fact that there was no improvement in survival with the experimental regimen was disappointing, but these findings are important as we continue to navigate ways to improve survival for this devastating disease," said Jyoti Patel, MD, lead author of the study and an associate professor in Medicine-Hematology/Oncology at Northwestern University in Chicago. "It is important to note that both regimens demonstrated tolerability, although their toxicities differed. These differences can be important for our patients."

###

The abstract, "A Randomized, Open-label, Phase 3, Superiority Study of Pemetrexed (Pem) + Carboplatin (Cb) + Bevacizumab (B) Followed by Maintenance Pem + B versus Paclitaxel (Pac) + Cb + B Followed by Maintenance B in Patients (pts) with Stage IIB or IV Non-squamous Non-small Cell Lung Cancer (NS-NSCLC)," will be presented during the Plenary Session at 12:30 p.m., Central time on September 7, 2012. To speak with Jyoti Patel, MD, please call Michelle Kirkwood or Nicole Napoli on September 6-8, 2012, in the press office at the Chicago Marriott Downtown Magnificent Mile at 312-595-3188. You may also email them at michellek@astro.org or nicolen@astro.org.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-09/asfr-scp090612.php

new hunger games trailer sasquatch david choe national wear red day gunner kiel gunner kiel groundhog

FERC Accuses Deutsche Bank Of Power Market Manipulation In California

Sorry, Readability was unable to parse this page for content.

Source: http://www.theenergydaily.com/publications/ed/8461.html

space ball drops on namibia matt barkley melanie amaro x factor boise state jordans prometheus movie posterior

Thursday, September 6, 2012

In Peterson trial, jurors quickly confront hearsay

FILE - In this May 8, 2009 file photo, former Bolingbrook, Ill., police sergeant Drew Peterson arrives at the Will County Courthouse in Joliet, Ill., for his arraignment on charges of first-degree murder in the 2004 death of his former wife Kathleen Savio, who was found in an empty bathtub at home. Attorneys will deliver closing arguments at Drew Peterson?s trial Tuesday, after which jurors will begin deliberations on whether the state proved the former Illinois police officer murdered his third wife. The sides make their final pitches after five weeks of testimony about the 2004 death of Kathleen Savio, whose body was found in a dry bathtub of her suburban home outside Chicago with a gash on the back of her head. (AP Photo/M. Spencer Green, File)

FILE - In this May 8, 2009 file photo, former Bolingbrook, Ill., police sergeant Drew Peterson arrives at the Will County Courthouse in Joliet, Ill., for his arraignment on charges of first-degree murder in the 2004 death of his former wife Kathleen Savio, who was found in an empty bathtub at home. Attorneys will deliver closing arguments at Drew Peterson?s trial Tuesday, after which jurors will begin deliberations on whether the state proved the former Illinois police officer murdered his third wife. The sides make their final pitches after five weeks of testimony about the 2004 death of Kathleen Savio, whose body was found in a dry bathtub of her suburban home outside Chicago with a gash on the back of her head. (AP Photo/M. Spencer Green, File)

Members of Drew Peterson's defense team leave the Will County Courthouse, Tuesday, Sept. 4, 2012, in Joliet, Ill. after closing arguments in Peterson's murder trial. Peterson is charged in the 2004 death of his third wife Kathleen Savio. Jurors are expected to begin deliberating tomorrow. (AP Photo/M. Spencer Green)

Will County States Attorney James Glasgow enters court for jury instructions in the murder trial of former Bolingbrook police officer Drew Peterson, Wednesday, Sept. 5, 2012, in Joliet, Ill. Jurors are expected to begin deliberating on allegations the former suburban Chicago police officer murdered his third wife. (AP Photo/M. Spencer Green)

Joel Brodsky, attorney for former Bolingbrook police officer Drew Peterson, addresses the media upon leaving the Will County Courthouse, Tuesday, Sept. 4, 2012, in Joliet, Ill., after closing arguments in Peterson's murder trial. Peterson is charged in the 2004 death of his third wife Kathleen Savio. Jurors are expected to begin deliberating tomorrow. (AP Photo/M. Spencer Green)

Will County Assistant State's Attorney Kathleen Patton, center enters court for jury instructions in the murder trial of former Bolingbrook police officer Drew Peterson, Wednesday, Sept. 5, 2012, in Joliet, Ill. Jurors are expected to begin deliberating on allegations the former suburban Chicago police officer murdered his third wife. (AP Photo/M. Spencer Green)

(AP) ? As they began deliberations Wednesday, jurors in Drew Peterson's trial immediately zeroed in on the case's trickiest issue: whether to believe secondhand hearsay statements that would often be barred from consideration in a criminal court.

Because of a botched initial investigation, detectives collected no fingerprints, strands of hair or any other physical evidence in the death of Peterson's third wife. So Illinois legislators passed a law aimed specifically at the former suburban Chicago police officer. That allowed prosecutors to pursue a conviction based substantially on statements Peterson's ex-wives made to friends and acquaintances.

After less than two hours of deliberations, jurors sent a flurry of notes to the judge asking for transcripts relating to hearsay that implicated Peterson. Forty-year-old Kathleen Savio was found dead in her bathtub in 2004, her hair soaked in blood and a gash on the back of her head.

Hearsay is any information reported by a witness that is not based on the witness' direct knowledge.

During five weeks of testimony, witnesses described statements Savio allegedly made about threats from her estranged husband and statements Peterson's fourth wife, 23-year-old Stacy Peterson, made before she disappeared in 2007.

Some defense attorneys worry that the trial ? the first in Illinois history to rely so heavily on hearsay ? could fundamentally alter how prosecutors and defense attorneys handle murder cases in this state and around the country.

"The legal issues here are extraordinary," said Phil Turner, a Chicago defense attorney and former federal prosecutor. "If this sets a precedent, more people will get convicted because someone testifies that someone told them something."

Heading into the trial, prosecutors described the hearsay evidence as offering Savio and Stacy Peterson the opportunity to speak to jurors "from their graves."

But the challenge for the jury is deciding if those words ? recounted secondhand in court ? are believable.

In closing arguments, the prosecution said the fact that more than a half-dozen witnesses cited conversations with Savio and Stacy Peterson that implicated Drew Peterson made those statements all the more believable.

But defense attorney Joe Lopez said the women's comments were no more credible than water-cooler gossip.

"How many times are you at work and you hear someone say something about someone. They're lying!" he told the jury.

The defense has also lashed out at Savio and Stacy Peterson's own credibility.

Lead defense attorney Joel Brodsky told jurors at the start of the trial that Savio was "bonkers" and prone to wild exaggeration ? especially in the thick of her acrimonious divorce from Peterson in the years before she died.

One of the notes sent to the judge asked for transcripts of testimony from Stacy Peterson's pastor, Neal Schori, who presented some of the trial's most dramatic hearsay.

Stacy Peterson cried in a meeting with Schori not long before she vanished, he testified. She told Schori that Peterson got up from bed in the middle of the night and left the house around the time of Savio's death. At dawn, she saw him putting woman's clothes into a washing machine that weren't hers, Schori said.

"She was very scared," Schori told jurors.

Jurors also asked for transcripts of attorney Harry Smith, who testified that Stacy Peterson called him three days before her disappearance seeking advice on divorcing Peterson, who was 30 years her senior.

Smith was called by the defense in a bid to dent Stacy Peterson's credibility. He told jurors she asked about whether she could extort her husband by threatening to tell police he killed Savio.

But Smith's testimony seemed to backfire on the defense as he repeatedly stressed to jurors that Stacy Peterson sincerely believed Drew Peterson had killed Savio.

Kathleen Zellner, a defense attorney who observed some of the testimony, predicted that jurors would accept the hearsay as credible because the judge deemed it admissible.

"They won't agonize over it," she said. "I think they will just accept it on face value. They'll think, 'The judge wouldn't let it come in if it was mere water-cooler talk.'"

The reputation for tactlessness that Peterson earned during a national media blitz before his 2009 arrest could work against him now, added another Chicago attorney, Michael Helfand.

After Stacy Peterson vanished, her husband joked about organizing a "Win a Date with Drew" contest" and discussed appearing on a reality TV show about a Nevada brothel.

"If he were a more sympathetic person, jurors might say, 'Hey, we can't put a guy in prison on the based on" secondhand information, Helfand said. "That'd be persuasive if he wasn't perceived as a scumbag."

Though jurors appeared to leap immediately into the hearsay evidence, it became clear later in the day that they also hadn't resolved another critical question: Was Savio's death even a murder?

Jurors sent another note asking for photographs of Savio's body as it was found jammed into her bathtub. They also wanted autopsy photos, including one of Savio's skull cut away to reveal her brain.

Prosecutor Chris Koch told jurors Tuesday it would have been impossible for Savio to suffer the wound on the back of her head and 14 bruises on the front of her body unless someone had attacked her.

"How can you get (all those wounds) in one fall?" he asked. "You can't."

Lopez conceded that fatal slips in bathtubs are one in a million, but he insisted all the evidence suggests that's just what happened to Savio.

"Are you trying to tell me no one has ever slipped in a bathtub before?" he asked. "That's why they sell rubber mats with suction cups on them."

Peterson has pleaded not guilty to first-degree murder in Savio's death. He was charged only after Stacy Peterson disappeared and Savio's body was exhumed and reexamined. Her death was reclassified from an accident to a murder.

Prosecutors were barred from mentioning that Stacy Peterson is presumed dead and that her husband is the lone suspect in her disappearance, although he has never been charged.

___

Follow Michael Tarm at www.twitter.com/mtarm

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2012-09-05-Drew%20Peterson%20Trial/id-4bb3c968332d4cef8b60c403f26ede6e

conocophillips octomom dan savage new world trade center kellen moore guy fieri ryan braun

Nokia Lumia 920 Officially Revealed: PureView Camera, Wireless Charging, Snapdragon S4 Processor

lumia920Nokia has finally put weeks of speculation to rest at its New York press conference today, as the Finnish phone company just pulled back the curtains on its newest flagship handset: the Windows Phone 8-powered Lumia 920.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/9eG7VqLoalQ/

whitney houston in casket photo resolute national enquirer whitney houston casket photo jk rowling qnexa kingdom of heaven national enquirer whitney houston

100s of striking miners march on mine in SAfrica

(AP) ? Ululating women and hundreds of striking miners waving sticks are marching on the South African platinum mine where police killed 34 of their co-workers, pressing demands for higher wages.

Throbbing police helicopters patrolled the skies and armed police in bulletproof vests and riding in armored personnel carriers kept watch over the peaceful protesters , who were being joined along the march routes Wednesday by hundreds more people who broke branches off trees.

One man said all they want is a monthly minimum wage of R12,500 ($1,560).

The London-registered Lonmin PLC mine has warned that the strike that began Aug. 10 could cost 40,000 jobs if it continues. The mine remains shut down with fewer than 5 percent of miners turning up for work.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2012-09-05-South%20Africa-Mining%20Violence/id-e263af1690ce43028392bc86f01a2478

marine urination video hostess cadillac ats bain capital marines urinating haley barbour olivier martinez

Wednesday, September 5, 2012

Too Much Confrontation?: (Confronting Friends, Part 2) ? NYC Life ...

confronting a friendConfrontation with anyone, let alone our friends, can be difficult. One of the skills we hope to develop is how to speak up for ourselves and advocate for our needs with other people. This doesn?t only mean learning how to ask for what we want, but also learning how to confront others when we feel wronged or in some way upset by them.

When strengthening a previous area of personal weakness and developing a new skill, it is a common tendency to overcompensate. For example, if our previous difficulty was handling conflict or issues with confrontation, and we learn new skills to confront in a healthy manner, we may start confronting more often?than necessary, almost as if we seek opportunities for confrontation practice.

It often takes a struggle in this area before people realize that there?is?such thing as too much confrontation. It?s a good thing to be able to handle conflict in a healthy manner, but it?s not healthy or necessary to confront people every time we feel frustrated.

Even when you become the master of confrontation and handling conflict, it?s important to still choose battles wisely. Part of dealing with frustrations with other people is being able to internally sort out the issues to see what?s necessary to open up between you and the other person involved.

Why not just confront every issue with our new confrontation skills? Isn?t it important to communicate and not hold things inside?

It is important to communicate well, but it?s equally important to know when the interpersonal confrontation needs, or doesn?t need, to happen.?Part of being a good communicator is also understanding when it?s?not?necessary to confront and let something go.?

Remember, when we are annoyed or frustrated by something and we choose to raise the issue, we?re not opening the conversation only to say we are frustrated, we?re also looking for our friends to respond by adjusting their actions to accommodate this in the future. Each time we raise an issue, it?s asking for an accommodation to be made. If this is overdone, it could put stress on the relationship,?including putting the other person in the position of closing off to us and becoming more cautious around us rather than open.

When there is an issue that one could confront, it is good to first understand the issue internally, and then decide if this is an issue that?s worthy of addressing, or letting go.?Letting something go doesn?t mean that we should leave issues unresolved. On the contrary, it means that we choose?to actually?let it go,?without further need to confront. It?s those issues that we process internally that we are still are unable to resolve within ourselves that may need confrontation ? the issues where we can?t let go. However, if we find we?re having trouble letting go of issues on a regular basis, it?s possible that some outside help could be useful to understand our own internal process.

In every relationship or friendship, there comes a point when a person needs to make a decision to accept a person for his or her limitations, or decide to remove themselves from that person, if they are triggering constant emotional distress. Even if our every emotional need isn?t met in our relationships, using our confrontation skills in a healthy manner helps us to balance our relationships to where our primary needs are being met.

Confrontation photo available from Shutterstock

Source: http://therapynathan.wordpress.com/2012/09/04/too-much-confrontation-part-2/

awake mario batali lone ranger aaron brooks dave matthews band solar flares 2012 whitney houston will